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Center for Molecular Studies in Digestive and Liver Diseases Grants
January 27, 2009, Volume 55, No. 19

GI Division Pilot Grants: March 1

Request for Applications

Pilot grants dealing with one of the following topics:

1. Endoscopic based research in humans, emphasizing the integration of new technologies and GI diseases.

2. Cellular and tissue imaging and translation to GI diseases.

3. Population based studies (databases) as they relate to colon cancer screening.

4. Outcomes research for endocscopic technologies and imaging.

5. Improving the management of difficult polypectamy with conventional or advanced methods.

6. Interventional endoscopic diagnosis and therapy.

Applicants must be based at the University of Pennsylvania and should be at the level of Instructor or higher.  If an Instructor, there should be a letter of support (1 page) from your Department Chair or Division Chief.

Proposal Preparation
1. Submit all documents, in the format below, as one PDF file to amolli@mail.med.upenn.edu

· Cover Page–should include an abstract up to 500 words and list approved or pending IACUC/IRB protocols (see www.med.upenn.edu/gastro/ClinicalTrials.shtml)

• NIH Biographical Sketch

• NIH Other Support

• Specific Aims

• Preliminary Data

• Research Design and Methods

• Summary

• Bibliography–maximum of 1 page

• Budget–not to exceed $25,000 in direct costs

• Budget Justification

2. Proposal can be based at any school in Penn and are encouraged to be multidisciplinary in nature. The deadline for proposals is March 1, 2009. Proposals should have a start date of April 1, 2009, with a 1 year duration.

Award Terms
A final progress report is due one month after the close of the project period. The report will contain a one page synopsis of scientific progress, a list of resulting collaborations, publications, and grants. 

If you have any additional questions, please e-mail Angela Hay at amolli@mail.med.upenn.edu or contact her at (215) 573-8557.

—Anil Rustgi, Center for Molecular Studies in Digestive and Liver Diseases

Studies in Digestive & Liver Diseases— Pilot and Feasibility Grants: April 30

Purpose and Research Focus
The purpose of Penn’s Center for Molecular Studies in Digestive and Liver Diseases is to unite investigators with interests in digestive and liver physiology and disease and to stimulate others in the biomedical community to enter this area of research.  One of the most important aspects of this effort is the funding of Pilot/Feasibility Projects.

The Pilot/Feasibility Project should be related to the focus of the Center, which encompasses molecular studies on the biology or disease of the alimentary tract, pancreas, and liver.  Relevant investigations include those in developmental biology, nutrition, regulation of gene expression, growth, differentiation and carcinogenesis, the biology of stem cells, molecular genetics, gene therapy, and immunology, including growth factors and cytokines.

All faculty members of the University scientific community who meet the eligibility requirements below are invited to submit proposals. Applicants must be US Citizens or have permanent visas.

1. New investigators who have never held extramural support (R29, RO1, PO1).

2. Established investigators in other areas of biomedical research who wish to apply their expertise to a problem in digestive and liver disease.

3. Established digestive and liver investigators who wish to study an area that represents a significant departure from currently funded work.

4. Pilot project awardees are eligible for two years of funding; renewals are evaluated competitively.

Proposal Preparation

1. Submit all documents, in the format below, as one PDF to kimmeyer@mail.med.upenn.edu. Proposals are due Thursday, April 30, 2009.

2. Format

• Cover page: includes abstract of up to 250 words and list of approved or pending IACUC/IRB protocols.

• NIH biographical sketch

• NIH other support (provide full information; do not use modular format)

• Budget and justification: one year, $20,000; one page only

• Background, preliminary results, estimated core usage, research plan, and future directions; up to four pages total.

• Senior Investigators should indicate how this project represents a new direction in their research.

• References: one page only.

• Appendix: pertaining to preliminary data only, no reprints.

For additional information, please contact: Center for Molecular Studies in Digestive and Liver Diseases, tel:  (215) 573-4264, fax:  (215) 573-2024, e-mail: kimmeyer@mail.med.upenn.edu.

—Anil Rustgi, Center for Molecular Studies in Digestive and Liver Diseases



Almanac - January 27, 2009, Volume 55, No. 19