A new finding by University of Pennsylvania scientists has identified key steps that trigger the disintegration of cellular regulation that leads to cancer. Their discovery—that a protein called Exo70 has a split personality, with one form keeping cells under tight control and another contributing to the ability of tumors to invade distant parts of the body—points to new possibilities for diagnosing cancer metastasis.
Researchers at the University of Pennsylvania, Brown University and ETH Zurich have now used a series of experiments to develop a dynamic model of the stresses that stretch growing tissue.
Penn Med Team Reports on Study of First 59 Leukemia Patients Who Received Personalized Cellular TherapyDecember 07, 2013
Three and a half years after beginning a clinical trial which demonstrated the first successful and sustained use of genetically engineered T cells to fight leukemia, a research team from the Perelman School of Medicine at the University of Pennsylvania and the Children’s Hospital of Philadelphia will today announce the latest results of studies involving both adults and children with advanced blood cancers that have failed to respond to standard therapies.
University of Pennsylvania researchers have found a way of traversing the blood-brain barrier, as well as a similar physiological obstacle in the eye, the retinal-blood barrier, to significantly degrade brain plaques associated with Alzheimer's disease.
Penn in the News
Christopher Pierce from the School of Medicine is quoted on emerging theories on inheriting fear.
Wharton professor Kartik Hosanagar's upcoming book is quoted on the social influence of the Internet.
An article by David Zaring of Wharton on the pros and cons of an American financial regulation model.
Studies on MOOCs from GSE and the Office of the Provost offer insight into the growth and development of online learning.
Vice Provost Ezekiel Emanuel co-authors an op-ed on the benefits of reducing health-care costs.