In a new study from the University of Pennsylvania and National Institute of Dental and Craniofacial Research, scientists used an innovative technique to study how cells move in a three-dimensional matrix, similar to the structure of certain tissues, such as the skin. They discovered an entirely new type of cell movement whereby the nucleus helps propel cells through the matrix like a piston in an engine, generating pressure that thrusts the cell’s plasma membrane forward.
A Penn Medicine-developed drug has received orphan status in Europe this week for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare, life-threatening disease that causes anemia due to destruction of red blood cells and thrombosis.
Treating the rare disease MPS I is a challenge. MPS I, caused by the deficiency of a key enzyme called IDUA, eventually leads to the abnormal accumulation of certain molecules and cell death.
A graduate student at the Perelman School of Medicine created The Condom Pledge, a social media and lifestyle campaign that calls for young people around the world to promise to use condoms and share their oaths to do so.
Penn in the news
The Perelman School of Medicine’s David Casarett discusses his book Shocked: Adventures in Bringing Back the Recently Dead.
Daniel Weintraub of the Perelman School of Medicine comments on how psychiatric problems might be early symptoms of a movement disorder.
Undergraduates Collin Hill and Aaron Goldstein of the Wharton School and William Duckworth of the School of Engineering and Applied Science and School of Arts & Sciences alum Becca Goldstein are featured for developing a smartphone-app thermometer.
Jeanmarie Perrone of the Perelman School of Medicine praises new opioid restrictions set by the Drug Enforcement Administration.
Sleep research from Allan Pack of the Perelman School of Medicine is described.