Penn Medicine: Genomewide Screen of Learning in Zebrafish Identifies Enzyme Important in Neural Circuit
Researchers at the Perelman School of Medicine at the University of Pennsylvaniadescribe the first set of genes important in learning in a zebrafish model in the journal Neuron this week. “Using an in-depth analysis of one of these genes, we have already revealed an important relevant signaling pathway,” says senior author Michael Granato, PhD, a professor of Cell and Developmental Biology. “The proteins in this pathway could provide new insights into the development of novel pharmacological targets.”
In a study published in the journal Genes and Development, University of Pennsylvania researchers have filled in details of how an enzyme, through interactions with a network of nearly two dozen other genes, protects the integrity of the germ line by giving rise to a class of RNA molecules that are essential to sperm development.
Penn Medicine Immunotherapy Pioneer Carl June, MD, Awarded 2015 Paul Ehrlich and Ludwig Darmstaedter Prize
University of Pennsylvania cancer and HIV expert Carl June, MD,&
A study coming out in Science Translational Medicine and led by University of Pennsylvania School of Veterinary Medicine researchers has shown that cats with the rare disease Niemann Pick type C — which mirrors the human version of the disease — show vast improvements when treated with a compound called cyclodextrin.
Penn in the news
President Amy Gutmann, Presidential Bioethics Commission chair, writes about three key areas of ethical concern in neuroscience research and application.
Elaina Lin of the Perelman School of Medicine shares her perspective on fetal surgery and fetal pain research.
Katherine Nathanson of the Perelman School of Medicine is quoted about BRCA testing.
Susan Margulies of the Perelman School of Medicine speaks on the difficulty of studying brain injuries in infants.
Susan Domchek of the Perelman School of Medicine is quoted about cancer prevention options and Penn’s Basser Research Center is mentioned.