Perelman School of Medicine

Should We Charge Patients for Medical Research?

July 31, 2015

Ezekiel Emanuel of the Perelman School of Medicine and the Wharton School and Steven Joffe of the Perelman School of Medicine co-author an op-ed about the idea of patients being charged for medical research.

Article Source: New York Times

Penn Study Says Placebos Could Prolong Drugs' Effectiveness

August 4, 2015

Michael Perlis of the Perelman School of Medicine suggests that placebos, currently used mainly for control groups in clinical trials, may be worth another look for treatment and for chronic illnesses; they might be a key to increasing a drug’s lifetime effectiveness.

Article Source: Philadelphia Inquirer

Case Study Offers Clues on How Penn Medicine Is Trying to Transform Health care

August 4, 2015

Leaders of Lancaster County's largest health system have repeatedly cited the need to move the industry away from its current fee-for-service model as a key factor in their decision to become part of Philadelphia-based Penn Medicine.

Article Source:

Silence of the Lambs

August 1, 2015


Rebecca Wells and Michael Pack of the Perelman School of Medicine are featured for leading a study about biliary atresia in zebrafish and mammals.

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Media Contact:Karen Kreeger | | 215-349-5658July 30, 2015

Penn Medicine: Cell Aging Slowed by Putting Brakes on Noisy Transcription

Working with yeast and worms, researchers found that incorrect gene expression is a hallmark of aged cells and that reducing such “noise” extends lifespan in these organisms. The team published their findings this month in Genes & Development.

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Media Contact:Karen Kreeger | | 215-349-5658July 30, 2015

Penn Study Questions Presence in Blood of Heart-Healthy Molecules from Fish Oil Supplements

The importance of a diet rich in fish oils – now a billion dollar food-supplement industry -- has been debated for over half a century. A few large clinical trials have supported the idea that fish oils confer therapeutic benefits to patients with cardiovascular disease. Researchers think that hearts and blood vessels may benefit in part from their anti-inflammatory properties.

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Media Contact:Katie Delach | | 215-349-5964July 30, 2015

Penn Bioethicists Call for End to "Pay-to-Play" Clinical Research

Charging people to participate in research studies is likely to undermine the fundamental ethical basis of clinical research, according to a new paper written by bioethicists, including lead author Ezekiel Emanuel, MD, PhD, chair of the department of Medical Ethics and Health Policy at the Perelman School of Medi

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Media Contact:Karen Kreeger | | 215-349-5658July 28, 2015

Sleepy Fruitflies Get Mellow: Sleep Deprivation Reduces Aggression, Mating Behavior in Flies, Penn Study Finds

Whether you're a human, a mouse, or even a fruitfly, losing sleep is a bad thing, leading to physiological effects and behavioral changes. One example that has been studied for many years is a link between sleep loss and aggression. But it can be difficult to distinguish sleep loss effects from stress responses, especially in rodent or human models.

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Media Contact:Karen Kreeger | | 215-349-5658July 27, 2015

Penn Scientists Find That Flow Means "Go" for Proper Lymph System Development

The lymphatic system provides a slow flow of fluid from our organs and tissues into the bloodstream. It returns fluid and proteins that leak from blood vessels, provides passage for immune and inflammatory cells from the tissues to the blood, and hosts key niches for immune cells. How this system develops hasn’t been well understood, but now researchers from the Perelman School of Medicine at the University of Pennsylvania have found from experiments in mice that the early flow of lymph fluid is a critical factor in the development of mature lymphatic vessels.

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Media Contact:Anna Duerr | | 215-349-8369July 23, 2015

Penn Study Finds Link between Physician Training and Brand Name Prescribing

Physicians in training are twice as likely to order a costly brand-name statin (used to lower blood cholesterol levels) when supervised by senior physicians who prefer those medications in their own practice, according to a new study led by researchers at the