PHILADELPHIA — A team of researchers led by Samir Mehta, MD, chief of the Orthopaedic Trauma & Fracture Service at the Perelman School of Medicine at the University of Pennsylvania, has received a $2.5 million grant from the Congressionally Directed Medical Research Program (CDMRP), provided through the U.S.
Perelman School of Medicine
PHILADELPHIA — LAM, short for pulmonary lymphangioleiomyomatosis, affects about 1 in 10,000 women of childbearing age and is characterized by proliferation of smooth muscle-like cells in the lung, destruction of lung tissue, and growth of lymphatic vessels. The disease is caused by inactivation of either of two genes, TSC1 or TSC2, but to date no animal model has been able to replicate the pathologic features those mutations produce in humans.
Lee Sweeney of the Perelman School of Medicine comments on the results of a new experimental drug used with muscular dystrophy.
Gary Lichtenstein of the Perelman School of Medicine offers advice on chronic constipation.
PHILADELPHIA — The hormone prolactin is produced by the pituitary gland in the brain and then travels via the bloodstream to cells throughout the body, where it exerts multiple reproductive and metabolic effects, most notably on the breast where it is the master regulator of lactation. In recent years researchers have found that prolactin is also produced by some tissues outside the brain, however little is known about the functions of extra-pituitary prolactin or how its production is regulated in these tissues.
PHILADELPHIA -- Chyke Doubeni has been named the second Presidential Term Professor at the University of Pennsylvania. Doubeni, an expert on colorectal cancer and racial disparities in health care, is Presidential Term Associate Professor-Clinician Educator in the Department of Family Medicine and Community Health of Penn’s Perelman School of Medicine.