(PHILADELPHIA) – The discovery that high levels of high-density lipoprotein (HDL) cholesterol (the “good cholesterol”) is associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.
Perelman School of Medicine
PHILADELPHIA – Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), and frontotemporal lobar degeneration (FTLD) are characterized by protein clumps in brain and spinal-cord cells that include an RNA-binding protein called TDP-43. This protein is the major building block of the lesions formed by these clumps.
John Trojanowski of the School of Medicine expresses his enthusiasm for President Obama’s signing the National Alzheimer’s Project Act into law.
President Amy Gutmann, Executive Vice President Craig Carnaroli and Executive Vice President and Chief Scientific Officer of the School of Medicine Glen Gaulton are highlighted for their roles in improving the West Philadelphia area.
George Cotsarellis of the School of Medicine comments on the research he led regarding this new development.
PHILADELPHIA – Given the amount of angst over male pattern balding, surprisingly little is known about its cause at the cellular level. In a new study, published in the Journal of Clinical Investigation, a team led by George Cotsarelis, MD, chair of the Department of Dermatology at the University of Pennsylvania School of Medicine, has found that stem cells play an unexpected role in explaining what happens in bald scalp.
Kevin Volpp of the School of Medicine and the Wharton School discusses testing new approaches to health-insurance incentives.