PHILADELPHIA — For the past decade, researchers have tried to reprogram the identity of all kinds of cell types. Heart cells are one of the most sought-after cells in regenerative medicine because researchers anticipate that they may help to repair injured hearts by replacing lost tissue. Now, researchers at the Perelman School of Medicine at the University of Pennsylvania are the first to demonstrate the direct conversion of a non-heart cell type into a heart cell by RNA transfer.
Perelman School of Medicine
Daniel Rader of the Perelman School of Medicine comments on HDL cholesterol.
PHILADELPHIA — Humans produce billions of clot-forming platelets every day, but there are times when there aren’t enough of them, such as with certain diseases or during invasive surgery. Now, University of Pennsylvania researchers have demonstrated that a single drug can induce bone marrow cells called megakaryocytes to quadruple the number of platelets they produce.
Margaret Stineman and Joel Streim of the Perelman School of Medicine comment on how Dr. Stineman uses her personal disabilities to help others.
Kevin Volpp, David Dinges and Lisa Bellini of the Perelman School of Medicine discuss reducing the number of consecutive work hours for first-year residents.
Thomas Wadden of the Perelman School of Medicine says, “Weight regain remains the Achilles’ heel of all weight loss therapies.”