Jonathan Moreno of the Perelman School of Medicine and the School of Arts and Sciences writes an op-ed about American science.
Perelman School of Medicine
A Penn- and MIT-led team explained how rapamycin, a drug that extends mouse lifespan, also causes insulin resistance. The researchers showed in an animal model that they could, in principle, separate the effects, which depend on inhibiting two protein complexes, mTORC1 and mTORC2, respectively.
The study suggests that molecules that specifically inhibit mTORC1 may combat age-related diseases without the insulin-resistance side effect, which can predispose people to diabetes.
Judd Hollander of the Perelman School of Medicine said, "We have spent the past 30 years trying to find a simple test that will tell patients, right now, 'It's not your heart.'"
Valerie Garfield, of the Perelman School of Medicine is now a homeowner in West Philadelphia, thanks to the Penn Home Ownership Program and the city's Home Buy Now program.
Patients with end-stage liver disease complicated by the most common type of liver cancer — hepatocellular carcinoma (HCC) — are less likely to die or become too sick for a transplant while waiting for a new liver than those with other complications of end-stage liver disease, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The investigators say their findings should prompt a re-examination of the criteria used to prioritize liver transplant candidates.
Scott Halpern of the Perelman School of Medicine says, “The problem is, it’s not at all clear that donors after circulatory determination of death are truly dead.”
Judd Hollander of the Perelman School of Medicine is featured for a study on CT angiography.