Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge. Now, new research has identified a common genetic risk factor for heart failure in Caucasians that is also linked to kidney function.
Perelman School of Medicine
Daniel Metz of the School of Medicine is mentioned for his literature review on liver transplant for neuroendocrine tumor metastases.
Muredach Reilly of the School of Medicine is cited for leading a new study that shows having the blood type O might guard against cardiac arrest.
Certain Genetic Profiles Increase Risk of Coronary Artery Disease, While Others Increase Risk of Heart Attack
(PHILADELPHIA) – Coronary artery disease (CAD) is the single largest cause of death in adults in the United States. Until recently, the genetic basis of CAD has been largely unknown, with just a few proven genes (typically genes for cholesterol disorders) accounting for very little of the disease in the population.
Robert Berkowitz of the School of Medicine speaks about the new USDA guidelines for school lunches.
Daniel Rader of the School of Medicine comments on what helps prevent heart disease.
(PHILADELPHIA) – The discovery that high levels of high-density lipoprotein (HDL) cholesterol (the “good cholesterol”) is associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.