Perelman School of Medicine

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Media Contact:Stephanie Simon | | 215-349-5659 September 1, 2010

Preventive Surgeries Linked to Lower Risk of Cancer for Women with BRCA1/2 Gene Mutations

Women who have inherited mutations in the BRCA1 or BRCA2 (BRCA1/2) genes have substantially elevated risks of developing breast and ovarian cancer.  A study that will appear in the September 1 issue of The Journal of the American Medical Association (JAMA) reports that women with these inherited mutations who have had a prophylactic mastectomy or salpingo-oophorectomy (removal of the fallopian tubes and ovaries) had an associated decreased risk of breast cancer and ovarian cancer.

Spinal Taps May Be Useful in Predicting Brain Disorders

August 30, 2010

 Leslie Shaw of the School of Medicine is cited for his research on an early Alzheimer’s diagnostic tool.

Article Source: Los Angeles Times

First Tests for Stem Cell Therapy Are Near

August 29, 2010

John Gearhart of the School of Veterinary Medicine and the School of Medicine comments on the possible impact of stem-cell transplantation therapy.

Article Source: Washington Post

What Does It Mean to Be an Ant?

August 26, 2010

 Shelly Berger of the School of Medicine comments on a breakthrough genome study.

Article Source: Nature

Gaining on Death, Cooling Therapy Catches on Slowly

August 26, 2010

Benjamin Abella of the School of Medicine discusses hypothermia’s clinical uses in treating cardiac arrest.

Article Source: Reuters

'I Am Hatred': What Turns Someone Into a Psycho-Killer?

August 25, 2010

Adrian Raine of the School of Arts and Sciences and the School of Medicine is cited for his neurological research on psychopathic behavior.

Article Source: “Nightline” (ABC News)
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Media Contact:Karen Kreeger | 215-349-5658 | August 26, 2010

Genome Comparison of Ants Establishes New Model Species for Molecular Research

By comparing two species of ants, Shelley Berger, PhD, the Daniel S. Och University Professor at the University of Pennsylvania, and colleagues Danny Reinberg, PhD, New York University, and Juergen Liebig, PhD, Arizona State University, have established an important new avenue of research for epigenetics -- the study of how the expression or suppression of particular genes affects an organism's characteristics, development, and even behavior.

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Media Contact:Jessica Mikulski | | 215-349-8369August 26, 2010

Penn Study Sheds Light on How the Brain Transitions Between Sleep and Awake States Under Anesthesia

Despite the fact that an estimated 25 million patients per year in the U.S. undergo surgeries using general anesthesia, scientists have only been able to hypothesize exactly how anesthetics interact with the central nervous system. They previously thought that the processes of “going under” and waking up from anesthesia affected the brain in the same way.

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Media Contact:Karen Kreeger | | 215-349-5658August 26, 2010

Swimming Upstream: Molecular Approaches to Better Understand Male Infertility

Male infertility is a common medical problem, affecting millions of men in the United States annually. Its causes include an inability to make productive sperm. Now, using yeast as a model organism, researchers at the University of Pennsylvania School of Medicine are beginning to identify the molecular signals that could in part underlie that problem.

Click here to view the full release.

Researchers at University of Pennsylvania Find Possible Genetic Link to Lou Gehrig's Disease

August 26, 2010

John Trojanowski, Virginia Lee and Aaron Gitler of the School of Medicine and Nancy Bonini of the School of Arts and Sciences are featured for their research on a Lou Gehrig’s disease gene.

Article Source: Philadelphia Inquirer