PHILADELPHIA - A recently identified immune cell that directs other cells to fight infection plays a critical role in regulating the immune system in both health and disease. Researchers from the University of Pennsylvania School of Medicine have discovered how a stimulatory molecule and a protein found on the membrane of another immune cell make T helper 17 cells multi-taskers of sorts.
Perelman School of Medicine
John Trojanowski and Jason Karlawish of the School of Medicine discuss research developments.
Healthy sleepers who carry a specific gene variant are more likely to have disrupted sleep, according to University of Pennsylvania study published in the October 26, 2010 issue of Neurology®, the medical journal of the American Academy of Neurology.
SAN DIEGO -- Prostate cancer patients who receive intensity modulated radiation therapy (IMRT) are less apt to suffer serious gastrointestinal complications following their treatment than those who receive three-dimensional conformal radiotherapy (CRT), according to new research from the University of Pennsylvania School of Medicine. The study, which will be presented Nov.
PHILADELPHIA -– Researchers at the University of Pennsylvania have developed a new electronic method for detecting microRNA isolated from living cells. MicroRNAs are a class of small biomolecules that control gene expression into proteins, the “workers” of the cell. MicroRNAs act by binding to specific messenger RNAs that code for proteins, and, by doing so, inhibit protein synthesis.
When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins - they have to be processed first. One of those processes is called splicing, a mechanism by which non-coding gene sequences are removed and the remaining protein-coding sequences are joined together to form a final, mature messenger RNA (mRNA), which contains the recipe for making a protein.