University of Pennsylvania researchers have successfully genetically engineered the immune cells of 12 HIV positive patients to resist infection, and decreased the viral loads of some patients taken off antiretroviral drug therapy (ADT) entirely—including one patient whose levels became undetectable.
Even the mildest form of a traumatic brain injury, better known as a concussion, can deal permanent, irreparable damage. Now, an interdisciplinary team of researchers at the University of Pennsylvania is using mathematical modeling to better understand the mechanisms at play in this kind of injury, with an eye toward protecting the brain from its long-term consequences.
Whether it is playing a piano sonata or acing a tennis serve, the brain needs to orchestrate precise, coordinated control over the body’s many muscles. Moreover, there needs to be some kind of feedback from the senses should any of those movements go wrong.
With the number of city dwellers expected to double in the next 30 years, bringing the tally to 7 billion city inhabitants worldwide, urbanization poses a wide range of critical issues, including housing, education, food security, energy, crime, economic development, income equality and public health.
Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus makes migration easier but is worse at protecting the nucleus’ DNA compared to a stiffer nucleus.
|WHAT:||“Research to Practice: Building Scholarship Critical to Building a Sustainable Urban Future,” a discussion hosted by the Penn Institute for Urban Research and HUD-sponsored dialogue in advance of the U.S.|
Three University of Pennsylvania faculty members are among this year’s Sloan Fellowship recipients. Since 1955, the Alfred P. Sloan Foundation has granted yearly fellowships to early-career scientists and scholars whose achievements and potential identify them the next generation of scientific leaders.
Penn Study Finds Topiramate Reduces Heavy Drinking Among Patients Seeking to Cut Down on Alcohol Consumption
Heavy drinking is common in the United States and takes a personal and societal toll, with an annual estimated cost of $223.5 billion due to losses in workplace productivity, health care and criminal justice expenses.
Mental Health Patients up to Four Times More Likely to Be Infected with HIV, Penn Medicine Study Finds
People receiving mental health care are up to four times more likely to be infected with HIV than the general population, according to a new study published Feb.