Research

facebook twitter google print email
Media Contact:Steve Graff | stephen.graff@uphs.upenn.edu | 215-349-5653April 19, 2015

Immunotherapy Drug Pembrolizumab Shows Early Promise for Mesothelioma Patients, Penn Medicine Researchers Find

The PD-1 inhibitor pembrolizumab, a cancer immunotherapy drug, shrank or halted growth of tumors in 76 percent of patients with pleural mesothelioma, a rare and deadly form of cancer that arises in the outer lining of the lungs and internal chest wall, according to a new study from researchers in the 

facebook twitter google print email
Media Contact:Steve Graff | stephen.graff@uphs.upenn.edu | 215-349-5653April 19, 2015

New Combination of Immunotherapy Drugs is Safe, Shrinks Tumors in Metastatic Melanoma Patients, Penn Study Finds

Once again, researchers at Penn’s Abramson Cancer Center have extended the reach of the immune system in the fight against metastatic melanoma, this time by combining the checkpoint inhibitor tremelimumab with an anti-CD40 monoclonal antibody drug.

facebook twitter google print email
Media Contact:Steve Graff | stephen.graff@uphs.upenn.edu | 215-349-5653April 19, 2015

Penn Medicine: Investigational Personalized Cellular Therapy Tolerated Well by Patients with Advanced Mesothelioma, Ovarian and Pancreatic Cancers

Genetically modified versions of patients’ own immune cells successfully traveled to tumors they were designed to attack in an early-stage trial for mesothelioma and pancreatic and ovarian cancers at the Per

facebook twitter google print email
Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658April 20, 2015

Messenger RNA-associated Protein Drives Multiple Paths in T-cell Development, Penn Study Finds

RNA is both the bridge between DNA and the production of proteins that carry out the functions of life and what guides which and how much protein gets made.

facebook twitter google print email
Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658April 16, 2015

Penn Study Describes First Steps in Basic Biological Process

Understanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves.

facebook twitter google print email
Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604April 15, 2015

Mentally Stepping Back From Problems Helps Youth Deal With Negative Emotions, Penn Study Says

Adolescence is a time of frequent and intense emotional experiences, but some youth handle their emotions better than others. Why do some young people react adaptively while others ruminate?

facebook twitter google print email
Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604April 15, 2015

Penn Senior Adrian Lievano to Tackle Water Security in Kenya

blurb: 
Building prosthetic limbs and developing rain-water filtration systems may seem like they have nothing in common. But to Adrian Lievano, a University of Pennsylvania senior from Miami majoring in mechanical engineering and applied mechanics, there’s a synergy: In both cases, the user is the designer’s top priority.

By Madeleine Stone @themadstone       

(This is the second in a series of features introducing the inaugural Penn President’s Engagement Prize winners.)  

facebook twitter google print email
Media Contact:Amanda Mott | ammott@upenn.edu | 215-898-1422April 17, 2015

Arab Spring’s Demands for Democratic Reforms Has Precedence, Penn Senior Finds

blurb: 
University of Pennsylvania undergraduate Anwar Akrouk's senior thesis argues that the Arab Spring’s demand for democratic reform mirrors nationalism’s rise following World War I and the Ottoman Empire’s fall.

By Julie McWilliams

facebook twitter google print email
Media Contact:Anna Duerr | anna.duerr@uphs.upenn.edu | 215-349-8369April 13, 2015

Penn Medicine Pain Management Study Reveals Patient Confusion about Opioid Addiction

Emergency department patients have misperceptions about opioid dependence and want more information about their pain management options, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

facebook twitter google print email
Media Contact:Ron Ozio | ozio@upenn.edu | 215-898-8658 April 14, 2015

Donita Brady Appointed Presidential Professor at Penn

Donita Brady has been named the seventh Presidential Professor at the University of Pennsylvania, effective July 1.  She will be Presidential Assistant Professor of Cancer Biology in Penn’s Perelman School of Medicine.