PHILADELPHIA –- Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing gene therapies for inherited blindness caused by rod degeneration.
PHILADELPHIA –- Veterinary ophthalmology researchers from the University of Pennsylvania have used gene therapy to restore retinal cone function and day vision in two canine models of congenital achromatopsia, also called rod monochromacy or total color blindness.
Nanotechnologists at Penn and Columbia Reveal the Frictional Characteristics of Atomically Thin Sheets
PHILADELPHIA –- A team of nanotechnology researchers from the University of Pennsylvania and Columbia University has used friction force microscopy to determine the nanoscale frictional characteristics of four atomically-thin materials, discovering a universal characteristic for these very different materials. Friction across these thin sheets increases as the number of atomic layers decreases, all the way down to one layer of atoms. This friction increase was surprising as there previously was no theory to predict this behavior.
PHILADELPHIA – A team of cardiologists, materials scientists, and bioengineers have created and tested a new type of implantable device for measuring the heart’s electrical output that they say is a vast improvement over current devices. The new device represents the first use of flexible silicon technology for a medical application.
PHILADELPHIA – Psychologists led by the University of Pennsylvania have used implantable electrodes and a first-person driving game to identify the cells of the brain that indicate travel in a clockwise or counterclockwise motion, called “path cells.” The study will be published this week in the Proceedings of the National Academy of Sciences.
PHILADELPHIA –- An interdisciplinary team of physicists and geologists led by the University of Pennsylvania has made a major step toward predicting where and how large floods occur on river deltas and alluvial fans.
In a laboratory, researchers created a miniature river delta that replicates flooding patterns seen in natural rivers, resulting in a mathematical model capable of aiding in the prediction of the next catastrophic flood.
Double Agents: Penn Researchers Identify Immune Cells That Fight Parasites May Promote Allergies and Asthma
PHILADELPHIA –- Millions of people in both the developing and developed world may benefit from new immune-system research findings from the University of Pennsylvania School of Veterinary Medicine.
The Penn Vet researchers, studying how the immune system operates, have discovered a previously unidentified cell population that may be the body’s double-edged sword, fighting off parasitic infections but also causing the harmful immune responses that can lead to allergies and asthma.