Research led by Caryn Lerman of the Perelman School of Medicine is highlighted.
Nicotine Withdrawal Weakens Brain Connections Tied to Self-Control Over Cigarette Cravings, Penn Study Finds
People who try to quit smoking often say that kicking the habit makes the voice inside telling them to light up even louder, but why people succumb to those cravings so often has never been fully understood. Now, a new brain imaging study in this week’s JAMA Psychiatry from scientists in Penn Medicine and the National Institute on Drug Abuse (NIDA) Intramural Research Pro
Today, almost 80% of all city dwellers live in Asian cities. In "The Future of Urbanization: What Can We Learn from Asian Cities?" a panel will examine the challenges and opportunities of urban life in Asia and suggest lessons for cities around the globe.
Penn Medicine: Personalized Gene Therapy Locks Out HIV, Paving the Way to Control Virus Without Antiretroviral Drugs
University of Pennsylvania researchers have successfully genetically engineered the immune cells of 12 HIV positive patients to resist infection, and decreased the viral loads of some patients taken off antiretroviral drug therapy (ADT) entirely—including one patient whose levels became undetectable.
Even the mildest form of a traumatic brain injury, better known as a concussion, can deal permanent, irreparable damage. Now, an interdisciplinary team of researchers at the University of Pennsylvania is using mathematical modeling to better understand the mechanisms at play in this kind of injury, with an eye toward protecting the brain from its long-term consequences.
Whether it is playing a piano sonata or acing a tennis serve, the brain needs to orchestrate precise, coordinated control over the body’s many muscles. Moreover, there needs to be some kind of feedback from the senses should any of those movements go wrong.
With the number of city dwellers expected to double in the next 30 years, bringing the tally to 7 billion city inhabitants worldwide, urbanization poses a wide range of critical issues, including housing, education, food security, energy, crime, economic development, income equality and public health.
Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus makes migration easier but is worse at protecting the nucleus’ DNA compared to a stiffer nucleus.