Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells.
A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell’s energy factory. They report their findings this week in Cell.
It’s a long way from DNA to RNA to protein, and only about two percent of a person’s genome is eventually converted into proteins.
Bringing clarity to a decades-long debate, a national team of researchers led by experts from the Perelman School of Medicine at the University of Pennsylvania has found that adding clot-busting medications known as thrombolytics to conventional approaches when treating sudden-onset pulmonary embolism patients is associated with 47
A team of researchers led by Penn Medicine anesthesiologists have pinpointed the “top five” most common perioperative procedures that are supported by the least amount of clinical evidence, in an effort to direct providers to make more cost-effective treatment decisions.
When a woman experiences a stressful event early in pregnancy, the risk of her child developing autism spectrum disorders or schizophrenia increases. Yet how maternal stress is transmitted to the brain of the developing fetus, leading to these problems in neurodevelopment, is poorly understood.
In conjunction with the first White House Maker Faire being held today, the University of Pennsylvania signed a joint letter along with more than 150 other institutions, pledging support to foster a “generation of makers.” The letter details the need for young tinkerers, inventors and entrepreneurs to bring life to future innovations.
This fall, thanks to an anonymous $250,000 gift, the University of Pennsylvania‘s School of Engineering and Applied Science will be opening the AddLab, a new additive manufacturing facility that will feature a suite of state-of-the-art 3-D printing tools.
Robert W. Carpick
John Henry Towne Professor and Department Chair
Mechanical Engineering Faculty and Students
Tour of new additive manufacturing facility
Wednesday, June 18, 12-1 p.m.
Towne Building Room 187 (gather by the CyberCafe)
This fall, thanks to an anonymous $250,000 gift, the University of Pennsylvania‘s School of Engineering and Applied Science will be opening the AddLab, a new additive manufacturing facility that will feature a suite of state-of-the-art 3-D printing tools. Professor Robert Carpick, chair of the Department of Mechanical Engineering and Applied Mechanics, will lead a preview of the facility; other members of the department will demonstrate 3-D printers and the kinds of objects they can make.
The event is timed to coincide with the first White House Maker Faire and national "Day of Making," a celebration of America as a nation of tinkerers, inventors and entrepreneurs who are using cutting-edge technologies like 3-D printers, laser cutters, desktop machine tools and free, user-friendly design software, democratizing the act of making and enabling citizens to build just about anything.
“Penn's founder Benjamin Franklin was an author, diplomat, inventor, physicist, engineer, politician and printer,” Carpick said. “While we can only imagine what he would think of today's revolution in manufacturing that is being brought about by the advent of 3-D printing, we are sure that he'd be proud to see Penn making its mark in the area.”
The event is free and open to the public.