Research

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Media Contact:Lee-Ann Donegan | leeann.donegan@uphs.upenn.edu | 215-349-5660June 18, 2014

Penn Anesthesiologists Identify Top Five Practices that Could be Avoided

A team of researchers led by Penn Medicine anesthesiologists have pinpointed the “top five” most common perioperative procedures that are supported by the least amount of clinical evidence, in an effort to direct providers to make more cost-effective treatment decisions.

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194June 18, 2014

Penn Team Links Placental Marker of Prenatal Stress to Neurodevelopmental Problems

blurb: 
New findings by University of Pennsylvania School of Veterinary Medicine scientists suggest that an enzyme found in the placenta is likely playing an important role in translating stress experienced by a mother early in pregnancy into a reprogramming of her developing baby's brain.

When a woman experiences a stressful event early in pregnancy, the risk of her child developing autism spectrum disorders or schizophrenia increases. Yet how maternal stress is transmitted to the brain of the developing fetus, leading to these problems in neurodevelopment, is poorly understood. 

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Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604June 18, 2014

Penn Lends Support to National ‘Maker Movement’

In conjunction with the first White House Maker Faire being held today, the University of Pennsylvania signed a joint letter along with more than 150 other institutions, pledging support to foster a “generation of makers.” The letter details the need for young tinkerers, inventors and entrepreneurs to bring life to future innovations.

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Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604June 17, 2014

Preview of Penn Engineering’s New 3-D Printing Lab as Part of National ‘Day of Making’

This fall, thanks to an anonymous $250,000 gift, the University of Pennsylvania‘s School of Engineering and Applied Science will be opening the AddLab, a new additive manufacturing facility that will feature a suite of state-of-the-art 3-D printing tools.

Who

Robert W. Carpick

John Henry Towne Professor and Department Chair
Department of Mechanical Engineering and Applied Mechanics
School of Engineering and Applied Science          
University of Pennsylvania

Mechanical Engineering Faculty and Students

What

Tour of new additive manufacturing facility
Demonstration of 3-D printed objects
 

When

Wednesday, June 18, 12-1 p.m. 

Where

Towne Building Room 187 (gather by the CyberCafe)
Chancellor Walk Entrance
Accessible from 34th and Walnut streets

Details

This fall, thanks to an anonymous $250,000 gift, the University of Pennsylvania‘s School of Engineering and Applied Science will be opening the AddLab, a new additive manufacturing facility that will feature a suite of state-of-the-art 3-D printing tools. Professor Robert Carpick, chair of the Department of Mechanical Engineering and Applied Mechanics, will lead a preview of the facility; other members of the department will demonstrate 3-D printers and the kinds of objects they can make.

The event is timed to coincide with the first White House Maker Faire and national "Day of Making," a celebration of America as a nation of tinkerers, inventors and entrepreneurs who are using cutting-edge technologies like 3-D printers, laser cutters, desktop machine tools and free, user-friendly design software, democratizing the act of making and enabling citizens to build just about anything.

“Penn's founder Benjamin Franklin was an author, diplomat, inventor, physicist, engineer, politician and printer,” Carpick said. “While we can only imagine what he would think of today's revolution in manufacturing that is being brought about by the advent of 3-D printing, we are sure that he'd be proud to see Penn making its mark in the area.”

The event is free and open to the public.

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194June 16, 2014

Penn’s Margaret Bruchac Uses Unique Approach to Identify Native American Objects

blurb: 
Anthropology professor Margaret Bruchac's approach to research, which she refers to as “restorative methodologies,” involves tapping into multiple data streams, including oral tradition, university archives, anthropological publications, physical evidence, craft technologies and social memory.

Early American history is marked by multiple displacements of Native American peoples due to multiple removals from their original Indigenous territories. During the late 19th and early 20th centuries, anthropologists participated in other forms of removal by collecting Indigenous narratives and objects for museums.

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Media Contact:Lee-Ann Donegan | leeann.donegan@uphs.upenn.edu | 215-349-5660June 12, 2014

Penn Study Also Suggests Adding CPAP Therapy May Help with High Blood Pressure

Obesity and obstructive sleep apnea (OSA) tend to co-exist and are associated with a variety of cardiovascular risk factors, including inflammation, insulin resistance, abnormal cholesterol, and high blood pressure.

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Media Contact:Karen Kreeger | Karen.kreeger@uphs.upenn.edu | 215-349-5658June 12, 2014

Penn Study Describes New Models for Testing Parkinson's Disease Immune-based Drugs

Using powerful, newly developed cell culture and mouse  models of sporadic Parkinson’s disease (PD), a team of researchers from the Perelman School of Medicine at the University of Pennsylvania, has demonstrated that immunotherapy with specifically targeted antibodies may block the development and spread of PD pathology in the brain.

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194June 11, 2014

Gum Disease Bacteria Selectively Disarm Immune System, Penn Study Finds

blurb: 
In a new study, University of Pennsylvania researchers show that bacteria responsible for many cases of periodontitis cause an imbalance in the microbial community in the gums, with a sophisticated, two-prong manipulation of the human immune system.

The human body is comprised of roughly 10 times more bacterial cells than human cells. In healthy people, these bacteria are typically harmless and often helpful, keeping disease-causing microbes at bay. But, when disturbances knock these bacterial populations out of balance, illnesses can arise. Periodontitis, a severe form of gum disease, is one example.

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Media Contact:Lee-Ann Donegan | leeann.donegan@uphs.upenn.edu | 215-349-5660June 9, 2014

Lifetime Costs for Autism Spectrum Disorder May Reach $2.4 Million Per Patient, Penn Study Finds

Costs for a lifetime of support for each individual with autism spectrum disorder may reach $2.4 million, according to a new study from researchers from the Perelman School of Medicine at the University of Pennsylvania and the Children’s Hospital of Philadelphia.

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Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604June 9, 2014

Penn Research Develops ‘Onion’ Vesicles for Drug Delivery

blurb: 
University of Pennsylvania researchers have shown that a certain kind of molecule that has tree-like branches can self-assemble into drug delivery vehicles that have multiple with concentric layers of membranes.

One of the defining features of cells is their membranes. Each cell’s repository of DNA and protein-making machinery must be kept stable and secure from invaders and toxins. Scientists have attempted to replicate these properties, but, despite decades of research, even the most basic membrane structures, known as vesicles, still face many problems when made in the lab.