Sometimes even cells get tired. When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop "T cell exhaustion," becoming less effective and losing their ability to attack and destroy the invaders of the body.
In 1913 in Southern California, two 241-mile-long electric lines began carrying power from hydroelectric dams in the Sierra Nevada to customers in Los Angeles—a massive feat of infrastructure. In 1923, power company Southern California Edison upgraded the line to carry 220,000 volts, among the highest voltage lines in the world at the time.
Crystalline materials have atoms that are neatly lined up in a repeating pattern. When they break, that failure tends to start at a defect, or a place where the pattern is disrupted. But how do defect-free materials break?
Cattle in the United States are generally managed to either produce milk or to produce beef. However, in most of the world, cattle are counted on to do both in what are called dual-purpose production systems.
Susan Domchek of the Perelman School of Medicine, and a study co-author, is quoted about gene panel tests for cancer.
Penn Medicine Study Reveals Novel Use of 3-D Imaging Technique for Precise Measurement of Injectable Wrinkle Reducers
A three-dimensional imaging technique often used in the automotive and aerospace industries for accurate measurement may be useful to measure the efficacy of injectable wrinkle reducers such as Botox and Dysport, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
Penn Medicine: Wide Variability in Organ Donation Rates: Midwest Leads Nation in Highest Rates of Donations
More than 123,000 Americans are currently waiting for lifesaving organ transplants, but 21 patients die each day because there aren't enough organs to go around. New research shows wide variation in the number of eligible organ donors whose loved ones consent to organ donation across the country.
Dean of Penn’s Perelman School of Medicine: Precision Medicine is “Personalized, Problematic, and Promising”
The rapidly emerging field of precision medicine is a “disruptive innovation” that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson, MD, PhD, dean of the Perelman School of Medicine and executive vice president of the University of Pennsylvania for the Health System, in this week’s issue of the New England Journal of Medicine.
Penn Medicine Authors Emphasize Importance of Clinically Actionable Results in Genetic Panel Testing for Breast Cancer
HDL is the “good cholesterol” that helps remove fat from artery walls, reversing the process that leads to heart disease. Yet recent drug trials and genetic studies suggest that simply pushing HDL levels higher doesn’t necessarily reduce the risk of heart disease. Now, a team led by scientists from the Perelman School of Medicine at the University of Pennsylvania has shown in a large, forward-looking epidemiological study that a person’s HDL function—the efficiency of HDL molecules at removing cholesterol—may be a better measure of coronary heart disease risk and a better target for heart-protecting drugs.