Research

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Media Contact:Karen Kreeger | Karen.kreeger@uphs.upenn.edu | 215-349-5658December 26, 2012

Penn Team Developing New Class of Malaria Drugs Using Essential Calcium Enzyme

PHILADELPHIA — Calpain, a calcium-regulated enzyme, is essential to a host of cellular processes, but can cause severe problems in its overactivated state. It has been implicated as a factor in muscular dystrophy, AIDS, Alzheimer's disease, multiple sclerosis, and  cancer.  As such, finding and exploiting calpain inhibitors is an important area of research. 

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Media Contact:Jessica Mikulski | jessica.mikulski@uphs.upenn.edu | 215-349-8369December 26, 2012

Immune System Changes May Drive Aggressiveness of Recurrent Tumors, Penn Researchers Report

PHILADELPHIA – Nearly half of the 700,000 cancer patients who undergo surgical removal of a primary tumor each year suffer a recurrence of their disease at some point, and many of those patients will eventually die from their disease. The traditional view of recurrent tumors is that they are resistant to therapy because they’ve acquired additional genetic mutations that make them more aggressive and impervious to drugs.

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194January 2, 2013

La’Toya Latney Cares for the Feathered, the Scaly, the Slimy and the Furry at Penn Vet

La’Toya Latney’s grandmother has a photo from when Latney was about 5 years old. In it, she is sitting in front of the television, transfixed by a nature program on grizzly bears hunting salmon swimming upstream.

“At that time she said she knew I was going to be a veterinarian, so it’s been a long time coming for me,” says Latney.

Do Cell Phones Explain 1990s Drop in Crime?

December 20, 2012

John MacDonald of the School of Arts and Sciences comments on the collaborative research he conducted about how cell phones played a part in dropping crime rates in the 1990s.

Article Source: Newsworks

Successful Salespeople Have Moderate Temperaments

December 19, 2012

Adam Grant of the Wharton School is cited for studying social temperaments of salespeople.

Article Source: Scientific American

Dual-use Research: Self-censorship Is Not Enough

December 19, 2012

Jonathan Moreno of the Perelman School of Medicine and the School of Arts and Sciences co-authors an article about publishing “potentially dangerous research on flu viruses.”

Article Source: Nature.com
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Media Contact:Karen Kreeger | Karen.kreeger@uphs.upenn.edu | 215-349-5658December 19, 2012

Protein Kinase Akt Identified as Arbiter of Cancer Stem Cell Fate, According to Penn Study

PHILADELPHIA — The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death.

Guns as Public Health Problem: A Penn Professor Speaks Out

December 18, 2012

Susan Sorenson of the School of Social Policy & Practice shares her thoughts about the lack of funding for studies on guns.

Article Source: Newsworks

Law Profs Suggest Another Explanation for Lower Crime Rate: Ubiquitous Cellphones

December 19, 2012

Jonathan Klick of the Law School and John MacDonald of the School of Arts and Sciences are cited for their collaborative research to help explain lower crime rates.

Article Source:

Inherited Resistance to Cocaine

December 17, 2012

A Penn Medicine study on inherited resistance to cocaine addiction, led by Christopher Pierce, is featured.

Article Source: The Scientist