PHILADELPHIA — El Yunque rock is a majestic, anvil-shaped promontory that has been an icon of the island of Puerto Rico since pre-Columbian times. The barren rock, standing 3,412 feet high, protrudes above primary old growth forest and is enshrouded in clouds, swept constantly by the trade winds and frequently stricken by hurricanes. The rock receives an average of three rain showers a day and more than 14 feet of rain every year. Given Puerto Rico’s warm and dynamic tropical climate, El Yunque should be covered with vegetation and eroding rapidly.
PHILADELPHIA — Passing one’s genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals.
Shaun Harper of the Graduate School of Education comments on a report about college graduation rates among black men.
Amy Witkoski Stimpfel of the School of Nursing is quoted about a nurse-burnout study.
Penn Study: Targeting Downstream Proteins in Cancer-Causing Pathway Shows Promise in Cell, Animal Model
PHILADELPHIA — The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell’s powerhouse, making it dependent on the amino acid glutamine for survival. In fact, 40 percent of all “hard-to-treat” cancers have a mutation in the Myc gene.
Accordingly, depriving cells of glutamine selectively induces programmed cell death in cells overexpressing mutant Myc.
PHILADELPHIA -- One million American school children are homeless each year, and many more are thought to move frequently. A researcher from the University of Pennsylvania’s School of Social Policy & Practice is the lead author on a new longitudinal study linking homelessness and frequent moving with children’s achievement.
PHILADELPHIA — When a virus such as influenza invades our bodies, interferon proteins are among the first immune molecules produced to fight off the attack. Interferon can also play a role in suppressing tumor growth and the effects of autoimmune diseases, and doctors may use an artificial form of interferon to treat patients with certain cancers or multiple sclerosis. But even this approach sometimes fails when patients’ bodies reject the foreign interferon or growing resistant to its effects.
Marina Cuchel and Daniel Rader of the Perelman School of Medicine are quoted about helping develop a treatment for rare heart conditions.
Matthew Bidwell of the Wharton School is cited for his collaborative paper “Do Women Choose Different Jobs From Men? Mechanics of Application Segregation in the Market for Managerial Workers.”