Health & Medicine

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Media Contact:Karen Kreeger | Karen.kreeger@uphs.upenn.edu | 215-349-5658August 26, 2014

Drug for Rare Blood Disorder Developed at Penn Receives Orphan Drug Status from European Union

A Penn Medicine-developed drug has received orphan status in Europe this week for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare, life-threatening disease that causes anemia due to destruction of red blood cells and thrombosis.

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Media Contact:Karen Kreeger | Karen.kreeger@uphs.upenn.edu | 215-349-5658August 28, 2014

Penn Medicine Study: Attacking a Rare Disease at its Source With Gene Therapy

Treating the rare disease MPS I is a challenge. MPS I, caused by the deficiency of a key enzyme called IDUA, eventually leads to the abnormal accumulation of certain molecules and cell death. 

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194August 28, 2014

Penn-NIH Team Discovers New Type of Cell Movement in 3D Matrix

blurb: 
In a new study from the University of Pennsylvania and National Institute of Dental and Craniofacial Research, scientists used an innovative technique to study how cells move in a three-dimensional matrix, similar to the structure of certain tissues, such as the skin. They discovered an entirely new type of cell movement whereby the nucleus helps propel cells through the matrix like a piston in an engine, generating pressure that thrusts the cell’s plasma membrane forward.

For decades, researchers have used petri dishes to study cell movement. These classic tissue culture tools, however, only permit two-dimensional movement, very different from the three-dimensional movements that cells make in a human body.

Lively Accounts Examining Death

August 25, 2014

The Perelman School of Medicine’s David Casarett discusses his book Shocked: Adventures in Bringing Back the Recently Dead.

Article Source: New York Times
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Media Contact:Greg Richter | gregory.richter@uphs.upenn.edu | 215-614-1937August 25, 2014

Penn Study Shows 25 Percent Fewer Opioid-Related Deaths in States Allowing Medical Marijuana

On average, states allowing the medical use of marijuana have lower rates of deaths resulting from opioid analgesic overdoses than states without such laws. Opioid analgesics, such as OxyContin, Percocet and Vicodin, are prescribed for moderate to severe pain, and work by suppressing a person’s perception of pain.

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Media Contact:Lee-Ann Donegan | leeann.donegan@uphs.upenn.edu | 215-349-5660August 22, 2014

Penn Study: Electronic Alerts Significantly Reduce Catheter-Associated Urinary Tract Infections

A Penn Medicine team has found that targeted automated alerts in electronic health records significantly reduce urinary tract infections in hospital patients with urinary catheters. In addition, when the design of the alert was simplified, the rate of improvement dramatically increased.

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Media Contact:Jill DiSanto | jdisanto@upenn.edu | 215-898-4820August 20, 2014

Taking ‘The Condom Pledge’: Penn Student’s Project Leads to Global Changes

blurb: 
A graduate student at the Perelman School of Medicine created The Condom Pledge, a social media and lifestyle campaign that calls for young people around the world to promise to use condoms and share their oaths to do so.

Jason Parad is changing lives, and he’s doing it with condoms.

Antiperspirants May Alter Your Armpit Bacteria – but For Better or Worse?

August 14, 2014

Elizabeth Grice of the Perelman School of Medicine comments on the use of deodorants and antiperspirants.

Article Source: Huffington Post
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Media Contact:Lee-Ann Donegan | leeann.donegan@uphs.upenn.edu | 215-349-5660August 18, 2014

Penn Study Finds Dopamine Replacement Therapy Associated with Increase in Impulse Control Disorders Among Early Parkinson's Disease Patients

New Penn Medicine research shows that neuropsychiatric symptoms such as depression, anxiety and fatigue are more common in newly diagnosed Parkinson’s disease (PD) patients compared to the general population.

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Media Contact:Lee-Ann Donegan | leeann.donegan@uphs.upenn.edu | 215-349-5660August 13, 2014

Drug-Induced Endoscopy Is Safe for Those With Sleep Apnea, Penn Study Finds

blurb: 
Researchers from Penn Medicine have developed a safe and effective technique for inducing sleep in patients with severe obstructive sleep apnea.

Researchers from Penn Medicine have developed a safe and effective technique for inducing sleep in patients with severe obstructive sleep apnea.