Health & Medicine

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194October 2, 2014

DNA ‘Bias’ May Keep Some Diseases in Circulation, Penn Biologists Show

blurb: 
In a new study published in the American Journal of Human Genetics, University of Pennsylvania researchers Joseph Lachance and Sarah A. Tishkoff investigated a process called gene conversion in the context of the evolution of human populations. They found that a bias toward certain types of DNA sequences during gene conversion may be an important factor in why certain heritable diseases persist in populations around the world.

It’s an early lesson in genetics: we get half our DNA from Mom, half from Dad.

But that straightforward explanation does not account for a process that sometimes occurs when cells divide. Called gene conversion, the copy of a gene from Mom can replace the one from Dad, or vice versa, making the two copies identical.

Tongue Fat May Become Key in Treating Sleep Apnea

October 1, 2014

Richard Schwab of the Perelman School of Medicine says, “Tongue size is one of the physical features that should be eva

Article Source: Philadelphia Inquirer

Penn Medicine Has Made 75 Apps to Make Its Hospitals Run Better

September 26, 2014

Penn Medicine is highlighted for developing apps, such as Connexus, that assist doctors and nurses with patient data.

Article Source: Technical.ly Philly

Antibiotics ‘Linked to Childhood Obesity’

September 30, 2014

Charles Bailey of the Perelman School of Medicine comments on how repeated courses of antibiotics are linked to childho

Article Source: BBC News

New Smart Catheters Help Doctors Navigate the Heart

September 28, 2014

Francis Marchlinski and David Frankel of the Perelman School

Article Source: Philly.com
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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658September 25, 2014

Penn Researchers Explain How Ends of Chromosomes Are Maintained for Cancer Cell Immortality

Maintaining the ends of chromosomes, called telomeres, is a requisite feature of cells that are able to continuously divide and also a hallmark of human cancer.

What Is Frontotemporal Dementia, and Is It Inheritable?

September 29, 2014

Murray Grossman of the Perelman School of Medicine explains frontotemporal dementia.

Article Source: Boston Globe

Health: Vitamin D Shows Promise for Local Patients Battling One of the Deadliest Cancers

September 26, 2014

Peter O’Dwyer of the Perelman School of Medicine talks about testing vitamin D injections in addition to aggressive che

Article Source: CBS Philly

More Women Skip Some Prenatal Tests After Learning About Risks

September 23, 2014

Debbie Driscoll of the Perelman School of Medicine comments on women who choose prenatal screenings.

Article Source: National Public Radio
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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194September 25, 2014

Penn-led Study Ties Aging to Oxidative Damage in Mitochondria

blurb: 
In a new study, University of Pennsylvania scientists used innovative techniques to find evidence that oxidative damage in mitochondria — the small compartments in cells that convert food to energy — may play a role in the aging process.

As long as humans have been alive, they’ve been seeking ways to extend life just a little longer. So far no one has found the fountain of youth, but researchers have begun to understand how humans age, little by little, offering hope for therapies that may blunt the effects of time on the body.