Health & Medicine

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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658July 2, 2015

Penn Medicine: Genetic Variation Determines Protein’s Response to Anti-diabetic Drug

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals.

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194July 8, 2015

Disrupting Cells’ ‘Powerhouses’ Can Lead to Tumor Growth, Penn Study Finds

blurb: 
A study by University of Pennsylvania researchers implicates defects in mitochondria, the energy-production centers of cells, as playing a key role in the transition from normal to cancerous.

Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.

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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658July 6, 2015

Penn Study Suggests Future Precision Medicine Approach to Treating Metabolic Syndrome, Related Disorders

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals.

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Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604July 6, 2015

Penn Researchers Answer Question about Nematode Behavior: Nature, Nurture, or Physics?

blurb: 
Nature versus nurture is an age-old question in biology, centering on whether a given trait is determined by an organism’s genes or by its environment. Most times the answer is “both,” but research at the University of Pennsylvania has found one trait in particular that is not easily described by either.

By Sarah Welsh

Nature versus nurture is an age-old question in biology, centering on whether a given trait is determined by an organism’s genes or by its environment. Most times the answer is “both,” but research at the University of Pennsylvania has found one trait in particular that is not easily described by either.

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194July 6, 2015

Blacklegged Tick Populations Have Expanded Via Migration, Penn Biologists Show

blurb: 
In a new study, biologists from the University of Pennsylvania found that blacklegged ticks moved into new areas of the Northeast from established populations, mainly through short-distance, local moves. The results shed light on patterns of disease spread and could have implications for strategies to control ticks in order to reduce disease.

Lyme disease cases are on the rise, with diagnoses occurring in areas that were historically Lyme-free. Scientists attribute the spread to the fact that populations of blacklegged ticks, which carry the bacteria that causes the disease, now flourish in areas once thought to be devoid of ticks.

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194 July 1, 2015

Penn Team Identifies Gene Responsible for Some Cases of Male Infertility

blurb: 
Oftentimes men with a type of infertility called azoospermia don’t know the underlying cause of their condition. But new research led by University of Pennsylvania scientists suggests that mutations in an X chromosome gene called TEX11 are responsible for a significant number of cases of infertility — an estimated 1 percent of cases of non-obstructive azoospermia.

In the most severe form of male infertility, men do not make any measurable levels of sperm. This condition, called azoospermia, affects approximately 1 percent of the male population and is responsible for about a sixth of cases of male infertility.

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Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604July 1, 2015

New Penn Center Will Investigate the Physics of Cancer Via $10M NIH Grant

Investigators at a new University of Pennsylvania research center will focus on key physical principles that underpin cancer’s development and growth.

Building a Better Valve

June 20, 2015

Howard Herrmann of the Perelman School of Medicine comments on patients treated with a transcatheter aortic valve replacement.

Article Source: New York Times

Couple’s Virology Research at Penn Was Pioneering

June 21, 2015

Gertrude and Werner Henle, husband-and-wife virologists of the Perelman School of Medicine and Children’s Hospital of Philadelphia, are featured.

Article Source: Philadelphia Inquirer
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Media Contact:Katie Delach | katie.delach@uphs.upenn.edu | 215-349-5964June 18, 2015

Penn Medicine Study Finds Participation in Research Studies Not Detrimental to Preterm Infants

Premature babies who are enrolled in clinical trials for therapies to treat and prevent complications from preterm birth are no more likely to die or experience poor outcomes than babies who are not trial participants, according to a retrospective analysis of more than 5,000 babies born before 29 weeks of gestation.