PHILADELPHIA - The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. Now, researchers at the University of Pennsylvania School of Medicine show that the protein has at least one other biochemical activity: controlling the metabolism of the sugar glucose, one of body's main sources of fuel.
Health & Medicine
Adrian Raine of the School of Arts and Sciences and the School of Medicine is cited for his research on neurocriminology.
Arthur Caplan of the School of Medicine comments on rationing organ donations.
PHILADELPHIA -- How would you like your car to be fixed by someone who had no knowledge of what it was like to drive? That’s the dilemma facing medical students whose training is focused on learning about medicine in medical school, but spend practically no class time learning about the real life obstacle course of the health care system which every one of their patients must learn to navigate.