PHILADELPHIA –- Bioengineers at the University of Pennsylvania have created a system to control the flexibility of the substrate surfaces on which cells are grown without changing the surface properties, providing a technique for more controlled lab experiments on cellular mechanobiology, an important step in the scientific effort to understand how cells sense and respond to mechanical forces in their environment.
Health & Medicine
University of Pennsylvania School of Medicine researchers have described a previously unknown biological mechanism in cells that prevents them from cannibalizing themselves for fuel. The mechanism involves the fuel used by cells under normal conditions and relies on an ongoing transfer of calcium between two cell components via an ion channel. Without this transfer, cells start consuming themselves as a way of to get enough energy.
Charles O'Brien of the School of Medicine discusses the benefit of HIV treatment among drug users.
Ann Slaughter of the School of Dental Medicine discusses dental health.
Arthur Caplan of the School of Medicine authors a piece on genetic testing.