PHILADELPHIA – Cells have their own version of the cut-and-paste editing function called splicing. Researchers at the University of Pennsylvania School of Medicine have documented a novel form of splicing in the cytoplasm of a nerve cell, which dictates a special form of a potassium channel protein in the outer membrane. The channel protein is found in the dendrites of hippocampus cells -- the seat of memory, learning, and spatial navigation -- and is involved in coordinating the electrical firing of nerve cells.
Health & Medicine
Arthur Caplan of the School of Medicine comments on the ethics of Arizona regulations on transplants.
Mariell Jessup of the School of Medicine comments on new developments in heart-failure treatment.
CHICAGO -- CPR quality is worse during in-hospital cardiac arrests occurring overnight than those that happen during the day, according to a new University of Pennsylvania School of Medicine study that will be presented at the American Heart Association's annual Scientific Sessions on November 14.
Penn-Led International Study Finds No Difference in Nonsuicide Mortality Between Two Anti-Psychotic Drugs
PHILADELPHIA - The potential for harmful side effects associated with anti-psychotic medications for treating schizophrenia is a frustration for mental-health professionals who must balance this with the positive benefits of drugs. For example, the issue of the antipsychotic drug ziprasidone lengthening the QTc interval, a possible indicator of life-threatening heart arrhythmias, has demanded much attention among clinicians since the drug was introduced in 2001.