University of Pennsylvania School of Medicine researchers have described a previously unknown biological mechanism in cells that prevents them from cannibalizing themselves for fuel. The mechanism involves the fuel used by cells under normal conditions and relies on an ongoing transfer of calcium between two cell components via an ion channel. Without this transfer, cells start consuming themselves as a way of to get enough energy.
Health & Medicine
Charles O'Brien of the School of Medicine discusses the benefit of HIV treatment among drug users.
Ann Slaughter of the School of Dental Medicine discusses dental health.
Arthur Caplan of the School of Medicine authors a piece on genetic testing.
PHILADELPHIA -– The mechanism by which a herpes virus invades cells has remained a mystery to scientists, but now research from Tufts University and the University of Pennsylvania reveals the unusual structure of a key member of the protein complex that allows a herpes virus to invade cells.
The new map details an essential piece of the herpes virus “cell-entry machinery,” providing scientists with a new target for antiviral drugs.
Sarah Tishkoff of the School of Medicine and the School of Arts and Sciences discusses “Jekyll-and-Hyde genetic variations."
William James of the School of Medicine discusses sunscreen’s effectiveness.