Health & Medicine

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194July 15, 2015

Penn Vet Team Shows a Protein Modification Determines Enzyme’s Fate

blurb: 
For the first time, researchers from the University of Pennsylvania School of Veterinary Medicine show how an amino acid tag on a protein has the power to greatly influence the function of an enzyme called PRPS2, which is required for human life and can become hyperactive in cancer.

The human genome encodes roughly 20,000 genes, only a few thousand more than fruit flies. The complexity of the human body, therefore, comes from far more than just the sequence of nucleotides that comprise our DNA, it arises from modifications that occur at the level of gene, RNA and protein.

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Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604July 17, 2015

Researchers at Penn Develop Scar-like Culture Systems to Understand and Treat Fibrosis

A scar might be a reminder of an accident or surgery, but the fibrous tissue that makes up a scar also forms after a heart attack and arises in solid tumors as well as in chronic diseases such as liver cirrhosis and muscular dystrophy. Implanted medical devices and materials are similarly surrounded by fibrous capsules that impede their function.  

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Media Contact:Evan Lerner | elerner@upenn.edu | 215-573-6604July 13, 2015

Imagination Institute at Penn Awards Nearly $3M to Develop ‘Imagination Quotient’

The Imagination Institute, based at the University of Pennsylvania’s Positive Psychology Center, has announced nearly $3 million worth of grants to researchers at 16 institutions. The grants are aimed at the development of better ways of assessing and promoting imagination and creativity.

My Q and A With Sleep Expert Mathias Basner on the Science of Sleep

July 8, 2015

Mathias Basner of the Perelman School of Medicine is interviewed about sleep deprivation, the relationship between work and sleep and other topics about the science of sleep.

Article Source: Huffington Post
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Media Contact:Steve Graff | stephen.graff@uphs.upenn.edu | 215-349-5653July 8, 2015

Remediating Abandoned, Inner City Buildings Reduces Crime and Violence in Surrounding Areas, Penn Study Finds

Fixing up abandoned buildings in the inner city doesn’t just eliminate eyesores, it can also significantly reduce crime and violence, including gun assaults, researchers from the University of Pennsylvania and Penn’s Perelman School of Medicine report in the first study to demonstrate the direct impact of building remediation efforts on crime.

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Media Contact:Anna Duerr | anna.duerr@uphs.upenn.edu | 215-349-8369July 7, 2015

Affordable Care Act Results in Dramatic Drop in Out-of-Pocket Prices for Prescription Contraceptives, Penn Medicine Study Finds

Average out-of-pocket spending for oral contraceptive pills and the intrauterine device (IUD), the two most common forms of contraception for women, has decreased significantly since the Affordable Care Act (ACA) took effect.

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Media Contact:Anna Duerr | anna.duerr@uphs.upenn.edu | 215-349-8369July 7, 2015

Serious Adverse Events Rare in Healthy Volunteers Participating in Phase I Drug Trials, Penn Medicine Study Finds

Many people believe that phase I trials with healthy volunteers are very risky and because they pose risks with no benefits, unethical. But how risky are such trials?

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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658July 2, 2015

Penn Medicine: Genetic Variation Determines Protein’s Response to Anti-diabetic Drug

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals.

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Media Contact:Katherine Unger Baillie | kbaillie@upenn.edu | 215-898-9194July 8, 2015

Disrupting Cells’ ‘Powerhouses’ Can Lead to Tumor Growth, Penn Study Finds

blurb: 
A study by University of Pennsylvania researchers implicates defects in mitochondria, the energy-production centers of cells, as playing a key role in the transition from normal to cancerous.

Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.

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Media Contact:Karen Kreeger | karen.kreeger@uphs.upenn.edu | 215-349-5658July 6, 2015

Penn Study Suggests Future Precision Medicine Approach to Treating Metabolic Syndrome, Related Disorders

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals.