Just as the brain forms memories of familiar faces, the immune system remembers pathogens it has encountered in the past. T cells with these memories circulate in the blood stream looking for sites of new infection.
Health & Medicine
Anusha Kalbasi and Justin Bekelman of the Perelman School of Medicine are highlighted for research into the impact of radiation on prostate cancer patients.
Elective Surgery Is Associated with Lower Risk of Death than Drugs for Ulcerative Colitis Treatment, Penn Study Finds
Patients over 50 with ulcerative colitis (UC), a chronic disease of the colon, who undergo surgery to treat their condition live longer than those who are treated with medications, according to a new study from the Perelman School of Medicine at the University of Pennsylvania.
Stem cells are key for the continual renewal of tissues in our bodies. As such, manipulating stem cells also holds much promise for biomedicine if their regenerative capacity can be harnessed. However, understanding how stem cells govern normal tissue renewal is a field still in its infancy.
Hydraulic Fracturing Linked to Increases in Hospitalization Rates in the Marcellus Shale Region, According to Penn Study
Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research from the University of Pennsylvania and Columbia University published this week in PLOS ONE.
Vision-Restoring Gene Therapy Also Strengthens Visual Processing Pathways in Brain, According to Penn Study
Since 2007, clinical trials using gene therapy have resulted in often-dramatic sight restoration for dozens of children and adults who were otherwise doomed to blindness. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia (CHOP), have found evidence that this sight restoration leads to strengthening of visual pathways in the brain, published this week in Science Translational Medicine.
The human genome encodes roughly 20,000 genes, only a few thousand more than fruit flies. The complexity of the human body, therefore, comes from far more than just the sequence of nucleotides that comprise our DNA, it arises from modifications that occur at the level of gene, RNA and protein.
A scar might be a reminder of an accident or surgery, but the fibrous tissue that makes up a scar also forms after a heart attack and arises in solid tumors as well as in chronic diseases such as liver cirrhosis and muscular dystrophy. Implanted medical devices and materials are similarly surrounded by fibrous capsules that impede their function.
Mathias Basner of the Perelman School of Medicine is interviewed about sleep deprivation, the relationship between work and sleep and other topics about the science of sleep.