Researchers from the University of Pennsylvania and Michigan State University presented new preclinical data this week that evaluates the efficacy of a gene therapy treatment for achromatopsia, a rare inherited retinal disease that involves cone cells. The disease affects humans as well as dogs.
Health & Medicine
Researchers from the Perelman School of Medicine and the Penn Center for AIDS Research (CFAR) have been awarded $7.5 million over five years from the National Institutes of Health to initiate a multi-project HIV study investigating a new gene therapy approach to render immune cells of HIV positive patients resistant to the virus.
Medical Education Risks Becoming Two-Tiered Unless Strong Research Focus is Preserved, Argue Philadelphia Medical Leaders
For more than 100 years, exposing students to basic and clinical research has been an essential component of a medical school education in the United States. However, today, new models of medical education in which research plays a minimal role are likely to create a two-tiered system of education, decrease the physician-scientist pipeline and diminish the application of scientific advances to patient care.
Penn Study Indicates that Gene Therapy Efficacy for LCA is Dynamic: Improvement is Followed by Decline in Vision
Gene therapy for Leber congenital amaurosis (LCA), an inherited disorder that causes loss of night- and day-vision starting in childhood, improved patients’ eyesight within weeks of treatment in a clinical trial of 15 children and adults at the Scheie Eye Institute at the Perelman School of Medicine at the University of Pennsylvania.
Off-Label Use of Device to Prevent Stroke in A-Fib Patients is Prevalent and Potentially Dangerous, According to Penn Medicine Study
The Lariat device, which has been cleared by the U.S.
Jay Giri of the Perelman School of Medicine says, “The Lariat is an absolutely ingenious piece of engineering… However,
By Madeleine Stone @themadstone
(This is the fifth and last in a series of features introducing the inaugural Penn President’s Engagement Prize winners.)
Penn Pioneer in Personalized Medicine Advocates that National Translational Medicine Consortia is Best Equipped to Drive Human Phenotyping for the Clinic
President Barack Obama launched the "Precision Medicine Initiative” this past winter during the State of the Union address, and politicians on both sides of the aisle applauded the announcement. Broadly, precision medicine is meant to help diagnose individuals more accurately and better tailor treatment according to their physiology.