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Guidelines And Policies

 

Protocol Preparation

The forms page will help you determine when and how to file the appropriate forms.

 

Preparing and Submitting a Protocol offers guidance.

 

 

Guidelines for specific procedures

If you require an exemption to any of the below Penn guidelines or policies, please complete an Exemption Form and submit to This e-mail address is being protected from spam bots, you need JavaScript enabled to view it for review.  If you protocol is in ARIES, please submit the Exemption Request directly in ARIES

Anesthetic Vaporizers & Gas Scavenging
Assigning Pain and Distress Levels to Animal Use Protocols Updated 12/19/14
Blood Collection - Common Sites for Blood Collection 

Carbon Dioxide Euthanasia of Rodents

EAE and Other Demyelinating Diseases in Rodents 
Egg and Oocyte Harvest from Laboratory Frogs (Xenopus Laevis) 

Euthanasia of Mouse and Rat Fetuses and Neonates

(For euthanasia of neonates 7 days or older, please refer to the Carbon Dioxide Euthanasia of Rodents guidelines)

Food and Fluid Regulation in Nonhuman Primates

Food and Fluid Regulation in Rodents
Humane Intervention and Endpoints for Laboratory Animal Species Updated 12/9/14
Large Animal Anesthesia and Analgesia Formulary Updated 12/9/14

Literature Search for Alternatives 

Monoclonal and Polyclonal Antibody Production
Mouse Anesthesia and Analgesia Recommendations

Mouse Breeding and Cage Density

Prolonged Restraint
Rapid Cooling to Induce Euthanasia of Zebrafish
Rat Breeding and Cage Density

Recordkeeping for USDA Species 

Rodent Genotyping Methods
Rodent Identification
Rodent Injections for Delivery of Experimental Agents

Rodent Survival Surgery 

Rodent Tumor and Cancer Models Updated 12/19/14
Tribromoethanol Use in Mice & Rats 
USDA Species Surgery Guideline
Use Of Complete Freund's Adjuvant in Laboratory Animals
Use of Neuromuscular Blocking Agents in Animals 

 

Species Specific Zoonoses Fact Sheets

  

Policies related to the animal research program

Adoption of University Animals
Animal Facilities Updated 12/19/14
Assuring Consistency Between Grants and Protocols
Canine Exercise and Socialization
Facility Visitation New 12/19/14
Investigation of Animal Welfare Concerns New 3/5/14
Management of Controlled Substances Updated 2/24/15
Policy on Who May Be a Principal Investigator on a Protocol

Post-Approval Monitoring Updated 3/4/15

Procurement of Animal Species (coming soon)
Protocol Review 

Reporting Animal Welfare Concerns Updated 2/25/14

Satellite Housing

Social Housing New 12/19/14

Social Housing of Nonhuman Primates Updated 12/9/14
Taking Images of Research Animals (coming soon)

Use and Disposal of Expired Drugs or Materials

Use of Non-Pharmaceutical Grade Compounds 

 
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