Guidelines And Policies

Protocol Preparation

The forms page will help you determine when and how to file the appropriate forms.

Preparing and Submitting a Protocol offers guidance.

Guidelines for specific procedures

If you require an exemption to any of the below Penn guidelines or policies, please complete an Exemption Form and submit to This e-mail address is being protected from spam bots, you need JavaScript enabled to view it for review.  If you protocol is in ARIES, please submit the Exemption Request directly in ARIES . 

Blood Collection - Common Sites for Blood Collection

Rodent Tumor Production

The Use Of Complete Freund's Adjuvant in Laboratory Animals

MonoClonal and Polyclonal Antibody Production

Food/Fluid Regulation in Rodents

Mouse Breeding and Cage Density   Rat Breeding and Cage Density

Food and Fluids Regulation in Nonhuman Primates

Prolonged Restraint

Carbon Dioxide Euthanasia of Rodents

Repeated Harvesting Of Oocytes From Xenopus Laevis

Rodent Survival Surgery  Rodent Anesthesia Record Template Rodent Postoperative Monitoring Template

Recordkeeping for USDA Species USDA Sample Anesthesia Chart

Anesthetic Vaporizers & Gas Scavenging

Rodent Anesthesia and Analgesia Formulary

Tribromoethanol Use in Mice & Rats

Assigning Pain and Distress Levels To Animal Use Protocols

Literature Search for Alternatives Searching for Alternatives Attachments

EAE and Other Demyelinating Diseases in Rodents

Rapid Cooling to Induce Euthanasia of Zebrafish

Rodent Genotyping Methods

Large Animal Anesthesia and Analgesia Formulary

Housing Laboratory Animals in the Study Area   Request paper form - Use this paper request form for pre-existing paper protocols. ARIES Submissions should submit Housing Requests through ARIES

Use of Neuromuscular Blocking Agents in Animals

USDA Species Surgery Guideline

Rodent Identification

Humane Intervention and Endpoints for Laboratory Animal Species

Guideline for the euthanasia of mouse and Rat Fetuses and Neonates (Extermal Link)

Rodent Injections for Delivery of Experimental Agents

Species Specific Zoonoses Fact Sheets

Policies related to the animal research program

Review and Investigation of Animal Welfare Concerns Reporting Animal Welfare Concerns

Adoption Policy for University Animals

Facility Visitation

IACUC Policy on who may be a Principal Investigator on a Protocol.

Taking, Storing and Destroying Compliance and Inspection Photographs

Procurement of Animal Species

Policy on Expired Drugs and Materials

Policy on Assuring Consistency Between Grants and Protocols

Canine Exercise and Socialization

Social Housing of Nonhuman Primates

Policy on Animal Facilities

Policy on Satellite Housing  Satellite Housing Review Flowchart