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IACUC Assurance


The Federal Government Animal Welfare Assurance for the University of Pennsylvania (Reference Assurance # D16-00045 (A3079-01)) is valid through July 31, 2018.  



The University Of Pennsylvania Perelman School Of Medicine and the School of Veterinary Medicine are both fully accredited by AAALAC International (AAALACi).  The PSOM was first accredited in July 1999, with the most recent AAALAC site visit occurring in January 2015.  The SVM was first accredited in July 2016. 



Animal Welfare Reporting

The Institutional Animal Care and Use Committee (IACUC) reviews and investigates concerns involving the care and use of animals resulting from reports by research and facility personnel or by public compliants.  Please make sure the Animal Welfare Reporting notice is posted in any laboratory, housing or procedure area where animals are used.


The IACUC encourages the prompt (within 24 hours) reporting of concerns or incidents related to animal welfare.  Allegations should be detailed and specific, and be accompanied by supporting documentation when possible, to allow for a thorough investigation.  All concerns will be reviewed regardless of how they are received.  Reports may be communicated anonymously.  Reports may be made by email or telephone to OAW senior staff.  Anonymous reports may be submitted to P-COMPLY (215-726-6759).



Post Approval Monitoring Program

Continuing IACUC oversight of animal research activities is required by federal laws, regulations, and policies.  As such, the IACUC has instructed the Office of Animal Welfare (OAW) compliance liaisons to perform post-approval monitoring (PAM) of any animal care activities on campus.  Penn’s PAM program meets the criteria set by the federal regulations [AWR 2.31(d)(5)] and complies with the performance-based standard set forth in the Guide for the Care and Use of Laboratory Animals (henceforth referred to as the Guide). The OAW PAM program aims to enhance the animal care and use program by:

  • Providing a resource to the research community by disseminating information and answering questions;
  • Creating a collegial atmosphere of open dialogue between the research community and the IACUC;
  • Acknowledging compliant laboratories, identifying and helping resolve any gaps in standards, and assisting laboratories with maintaining compliance with federal and institutional policies/guidelines.  


The PAM program involves the following areas:

  • Review select protocol submissions where procedures occur outside a ULAR-managed location (i.e., survival surgery locations, animal housing). Compliance liaisons also review exemption submissions, which describe any deviation from the Animal Welfare Regulations, the Guide, or specific Penn policies, guidelines, or SOPs;
  • Perform general or observational PAMs of any animal care activities on campus with the purpose of documenting evidence of good performance. Compliance liaisons will assist in resolving unintentional non-compliances and acknowledge compliant laboratories on campus, all of which is overseen by the IACUC Compliance Subcommittee. Selection of observational PAMs is determine by the OAW, the IACUC, and by request of the PI to assist their laboratory.
  • Coordinate IACUC semi-annual site visits to ensure facilities meet federal and institutional standards (i.e., area maintenance, surgical locations and support areas, animal housing, recordkeeping);
  • Initiate investigation of reported animal welfare concerns under supervision of the IACUC Compliance Subcommittee.


Additionally, self-reporting animal welfare and compliance-related incidents is an important component of Penn’s PAM program. When deciding on how to best resolve the incident and prevent reoccurrence, due consideration is given to those individuals who self-identify and self-report potential issues to the IACUC.

The institution is expected to self-report animal welfare concerns and non-compliances to federal regulatory and accrediting agencies [OLAW NOT-OD-05-034].


The resources below can provide more information on PAM programs:

   Copyright 2008 University of Pennsylvania Office of Regulatory Affairs | 3624 Market Street, Suite 301 S., Philadelphia, PA 19104-6006
   Phone: 215-898-2615    Fax: 215-746-6308.
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