2006 Pilot Study Announcement:
Penn Alzheimer's Disease Core Center (ADCC)
with The Institute for Medicine and Engineering (IME)

The National Institute on Aging (NIA) of the National Institutes of Health (NIH) has just notified the  University of Pennsylvania that the competing renewal application of the Penn Alzheimer’s Disease Core Center (ADCC) will be funded by NIA for years 16-20 thereby enabling the Penn ADCC to continue to fund two one year Pilot grants on biomedical, epidemiological or behavioral research on Alzheimer’s disease (AD) and related neurodegenerative disorders in basic science or clinical areas. In a continuing joint effort with the Institute for Medicine and Engineering (IME), a third Pilot grant also will be funded to support research on the etiology, pathogenesis, diagnosis or management of AD or related conditions that bridges medicine and engineering. The purpose of these Pilots  is to assist Penn faculty, especially young investigators and those new to the field, to obtain preliminary data to serve as the basis of a grant application to the NIH or other public or private agencies.  Each Pilot will be funded up to a level of $30,000 for personnel and supply costs, but not equipment or instruments.

A committee of ADCC/IME members will review all proposals. Funding depends on scientific merit, and the likelihood that the Pilots will lead to independent funding to continue the research. Principal Investigators must be fulltime faculty of the University of Pennsylvania and collaboration with other departments is strongly encouraged. Priority will be given to:

• Faculty in the early stages of their career who seek to enter the arena of research on AD and related neurodegenerative disorders

• Senior faculty who intend to shift their research emphasis towards research on AD and related neurodegenerative disorders

Application Process:

Applications should be formatted basically in the style of an NIH PHS 398 format.  However, please substitute NIH face page with a title page.  Applications should be 5 pages (exclusive of biosketches, literature cited, etc. as in PHS 398). Animal and/or IRB protocols may be pending.   For more information contact Kevin Davies at (215) 662-4474. Suggested page distributions are:

1. Title Page (not the NIH face page) showing the title of grant, name of P.I., affiliation, address & phone nos. 
2. Budget (costs for personnel, supplies, but not equipment)
3. NIH Style Biosketch
4. Specific Aims
5. Background and Significance
6. Preliminary Studies
7. Experimental Design & Methods
8. Human Subjects (if applicable and protocol may be pending)
9. Vertebrate Animals Sections (if applicable and protocol may be pending)
10. Consultants (if applicable)
11. Consortium Contractual Arrangements (if applicable)
12. Literature Cited
13. Certification of Patient Oriented Research (if applicable) 

IT IS OBLIGATORY THAT PILOT AWARDEES PROVIDE A FINANCIAL AND RESEARCH PROGRESS REPORT AT THE END OF THE PILOT YEAR.   

APPLICATIONS DUE: Close of Business July 24, 2006

ANTICIPATED DATE OF AWARD AUGUST 1, 2006 (grant period is 11 months to coincide with fiscal year 16 of the Penn ADCC )

Submit original and 5 copies to:    

Kevin Davies (215) 662-4474
University of Pennsylvania School of Medicine
Center for Neurodegenerative Disease Research
Department of Pathology & Laboratory Medicine
3rd Floor Maloney Bldg. HUP
3600 Spruce Street
Philadelphia, PA 19104-4283

Posted 6/13/06

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