|
"Deformable Shape Modeling for Biomedical Applications"
October 26, 2001,
11:00a.m.
GRASP Laboratory
318C, Large Conference Room
(3401 Walnut Street)
Abstract:
Deformable models have found widespread applicability in diverse fields
during the past 15 years. This talk will discuss deformable shape models
in
the context of two problems: computational anatomy and modeling soft
tissue
deformability for surgical applications. A shape-based approach to
deformable registration of brain images will be presented, which is
based on
matching geometric attributes calculated at different scales and
embedded in
a hierarchical framework. A framework for combining point distribution
models and biomechanics will also be presented, with the goal of
predicting
soft tissues deformations during surgery. Applications of these methods
to
large imaging studies are also presented, with emphasis on a
longitudinal
study of aging aiming at establishing quantitative criteria for early
prediction of Alzheimer's disease, using morphological and functional
measurements.
|
